United States
Sermorelin (acetate) CAS NO.516482-86-3
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Pure(1-10)Gram
- Product Details
Keywords
- A growth hormone-releasing hormone analog
- Peptide Hormone
- Somatotropin Releasing-Hormone
Quick Details
- ProName: Sermorelin (acetate)
- CasNo: 516482-86-3
- Molecular Formula: C149H246N44O42S ? XC2H4O2
- Appearance: A solid
- Application: RESEARCH AREAS Cancer Endocrinology ...
- DeliveryTime: 1-3days
- PackAge: Discreet
- ProductionCapacity: 1 Kilogram/Week
- Purity: ≥95%
- Storage: 20°C
- Transportation: Air Freights
- LimitNum: 0 Metric Ton
Superiority
1. Sermorelin (1 μg/kg, i.v.) increases serum GH levels in rats by approximately 17% compared with saline control after 15 minutes.
2. It also increases GH release in pigs when administered at a dose of 250 ng/kg
3. Sermorelin (1 μM) increases proliferation of NCI-H727 human bronchial carcinoid cells by 30% and increases vascular endothelial growth factor (VEGF) secretion.
4. It increases phosphorylation of focal adhesion kinase (FAK) and expression of VEGF in A549 lung cancer cells when used at a concentration of 0.1 μM.
5. Formulations containing sermorelin have been used to diagnose and treat growth hormone deficiency.
Details
Sermorelin is a 29-residue N-terminal analog of growth hormone-releasing hormone (GHRH) that retains the ability to stimulate growth hormone (GH) release.